Through one of the largest studies yet of Alzheimer’s disease (AD) patients and their brothers, sisters, and children, researchers at Mayo Clinic Jacksonville have found strong evidence that genes other than the well-known susceptibility risk factor APOE4 influence who is at risk for developing the neurodegenerative disease later in life.
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High blood pressure appears to be associated with an increased risk for mild cognitive impairment, a condition that involves difficulties with thinking and learning, according to a report in December issues of Archives of Neurology
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Alzheimer’s disease may progress more rapidly in people with high blood pressure or a form of irregular heartbeat called atrial fibrillation, according to results of a Johns Hopkins study published in the Nov. 6, 2007, issue of Neurology. The findings suggest that treating these conditions may also slow memory loss in people with Alzheimer’s.
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Amyloid plaques, the hallmark of Alzheimer’s disease, are clumps of fiber-like misfolded proteins which many experts think cause this devastating neurodegenerative disease. While effective treatment remains an elusive goal, new research by University of Illinois at Chicago chemists suggests a possible new approach.
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